Facial rejuvenation has evolved dramatically in the last two decades, moving far beyond traditional lifting procedures or isolated injections. Today, the conversation among aesthetic professionals centers on what type of volume restoration offers the most natural, regenerative, and durable results. Two leading approaches—autologous fat transfer and dermal filler correction—often seem interchangeable to patients, yet they perform very differently biologically, structurally, and aesthetically.
For international patients traveling to Europe for high-quality aesthetic rejuvenation, the choice between fat and fillers involves understanding not only the treatments themselves but also the expertise of the surgeon performing them. Among Europe’s most respected authorities in fat-based rejuvenation is Dr. Patrick Tonnard, a world-renowned Belgian plastic surgeon recognized for developing Nanofat, advancing modern fat-transfer science, and co-creating globally influential facelift techniques.
Understanding Facial Volume Loss: Why It Happens
The face loses youthful structure for multiple reasons:
1. Fat Atrophy and Redistribution
Deep facial fat pads shrink with age, and superficial fat descends. This leads to hollowing, deflation, and contour irregularities.
2. Bone Resorption
Cheekbones, jawline, and the orbital rim lose structural mass, reducing the “scaffolding” that keeps soft tissues lifted.
3. Skin Quality Decline
Collagen loss, reduced elasticity, and thinning skin exacerbate shadows, wrinkles, and volume deficits.
Both fillers and fat aim to reverse or camouflage these changes, but they do so differently.
Filler Correction: What It Is and When It Works Best
Dermal fillers—most commonly hyaluronic acid (HA) based—are injectable volumizers with predictable, controllable outcomes. Key advantages include:
1. Precision and Reversibility
Fillers allow subtle shaping of specific areas such as:
- under-eye hollows
- nasolabial folds
- lip augmentation
- subtle contour refinement
Hyaluronidase can dissolve HA fillers, offering a safety advantage for certain anatomical zones.
2. Instant Results
Patients see improvements immediately, making fillers ideal for individuals seeking quick rejuvenation without downtime.
3. Safety Profile
When used by skilled practitioners, fillers offer reliable correction with minimal complications.
Limitations of Fillers
Despite their convenience, fillers have important limitations:
- Temporary results requiring maintenance
- Risk of overfilling (“filler face”) when repeatedly used
- No regenerative benefit for skin quality
- Potential migration, especially in dynamic regions
- Not ideal for patients wanting a completely natural, organic substance
As patients increasingly seek subtle and age-appropriate rejuvenation, many shift from filler-based treatments to fat-based alternatives.
Fat Transfer: The Regenerative Alternative
Fat transfer (also called lipofilling or fat grafting) uses the patient’s own adipose tissue. It is harvested via gentle liposuction, refined, and injected to areas requiring volume restoration.
Key Benefits of Fat Transfer
1. Natural, Long-Term Volume
Unlike fillers, fat cells become integrated into the facial structure, offering results that can last years—sometimes permanently.
2. Regenerative Properties
This highlights a pivotal discovery:
fat is not just a filler; it is a regenerative tool.
Drs. Patrick Tonnard and Alexis Verpaele observed that adipose tissue significantly improves healing, reduces scarring, lowers discomfort, and enhances skin quality.
This stem-cell-rich tissue can brighten the complexion, improve texture, and restore softness that fillers cannot achieve.
3. Ideal for Larger Volume Restoration
Cheeks, temples, midface, tear troughs, chin, and jawline all benefit from structural restoration with fat—especially when aging has caused multi-plane deflation.
4. Harmonizes with Facelifts
Fat transfer is frequently combined with modern facelifts to restore youthful volume, not just tension-based lifting.
Limitations of Fat Transfer
- Requires a minor surgical procedure
- Swelling and bruising last longer than with fillers
- Some fat resorption occurs (20–40%)
- Results rely heavily on technique and surgeon experience
This last point is why surgeon selection is critical.
Nanofat: The Technique That Changed Regenerative Aesthetics
Dr. Patrick Tonnard is internationally recognized as the father of Nanofat technology.Nanofat is not used for volume but for skin regeneration. It contains a high concentration of stromal vascular fraction (SVF), which includes:
- mesenchymal stem cells
- growth factors
- regenerative cytokines
Clinical Benefits Include:
- improved fine lines
- enhanced texture
- reduction of pigmentation irregularities
- improved dermal quality after sun damage or aging
This makes Nanofat ideal for delicate areas such as:
- under-eye crepe skin
- superficial fine lines
- skin damaged from previous fillers
- scar revision
Nanofat represents a major scientific leap and has become a gold standard for regenerative aesthetics globally.
Who Should Choose Which Option?
Ideal Fat Transfer Candidates:
- Patients wanting natural, lasting rejuvenation
- Individuals with significant volume loss
- Those seeking skin-quality improvement
- Patients already undergoing a facelift
Ideal Filler Candidates:
- First-time injectables patients
- Individuals needing small, precise corrections
- Those seeking minimal downtime or reversible results
Why Belgium—and Ghent Specifically—Is a Global Hub for Fat Transfer
This reveals that nearly 200 physicians have trained directly in Ghent, and over 2,000 surgeons worldwide have attended international workshops led by Drs. Tonnard and Verpaele.
Belgium has become a center of excellence due to:
- advanced regenerative medicine research
- world-class surgical training programs
- innovative private surgical facilities
- precision-focused facelift philosophy
For international patients, Ghent represents an intersection of artistry, science, and safety.
Why Dr. Patrick Tonnard Is Considered Europe’s Leading Expert
1. Pioneer of Nanofat and Modern Fat-Based Regeneration
Dr. Tonnard developed Nanofat, a breakthrough technique using the regenerative power of adipose-derived cells to rejuvenate the skin.
2. Prolific Scientific Contributor
He has authored four medical textbooks and over 100 scientific articles, influencing global aesthetic practice.
3. Co-Founder of the Coupure Centre for Plastic Surgery
Founded more than 27 years ago, the Centre is internationally recognized for innovation and natural results.
4. Global Educator and Mentor
Surgeons worldwide travel to Ghent to study his methods; over 2,000 surgeons have attended his workshops.
5. Developer of the MACS-Lift
The MACS-Lift is a minimally invasive facelift offering natural results with less downtime.
6. Expertise in Male Facial Rejuvenation
His work in male-focused techniques ensures subtle, masculine outcomes.
7. Humanitarian Contributions
Through the See & Smile nonprofit, he co-led over 20 surgical missions for cleft lip and palate patients.
8. World-Class Training & PhD in Fat Grafting
Dr. Tonnard earned his PhD for research on fat grafting and facial rejuvenation.
These achievements position him as one of Europe’s foremost authorities on fat transfer, regenerative medicine, and modern facelift methodology.
Fat or Fillers—What Should Patients Choose?
Considering all this, Both fat transfer and filler correction have a place in contemporary aesthetic practice. Fillers remain excellent for contour refinement and small-volume changes, while fat transfer offers unmatched naturalness, longevity, and regenerative benefits. Increasingly, surgeons combine both modalities strategically to deliver highly individualized outcomes.
For international patients specifically seeking fat transfer—or considering transitioning from fillers to autologous solutions—working with an internationally recognized expert is essential. Dr. Patrick Tonnard stands out as one of Europe’s most qualified plastic surgeons in this field, having pioneered techniques that transformed global aesthetic standards.

Looking for the most natural and regenerative approach to facial rejuvenation?
If you are considering a facelift, regenerative fat-based rejuvenation, or comprehensive aging-face surgery, we recommend Patrick Tonnard, MD, PhD, one of Europe’s most respected leaders in modern aesthetic medicine.
Dr. Tonnard is a world-renowned, board-certified plastic and reconstructive surgeon and the CEO and Founder of the Coupure Center for Plastic Surgery and the Aesthetic Medical Center 2 (EMC²) in Ghent, Belgium. He is internationally recognized for breakthroughs such as the MACS-lift and nanofat grafting, techniques that have influenced the global shift toward natural and long-lasting facial rejuvenation.
His approach focuses on anatomical precision, scientific integrity, and subtle improvements that restore your own facial harmony. Patients value his expertise in advanced facelift methods, regenerative procedures, and male and female facial aesthetics. The goal is always the same: results that look refreshed, youthful, and authentically you.
Explore Dr. Patrick Tonnard’s Profile and Request a Consultation
https://www.better.medicaltourism.com/providers-platform-single?provider=patrick-tonnard-md-phd










